The death toll in the US from the novel coronavirus surpassed the 100,000 mark Wednesday, according to data compiled by Johns Hopkins University.
The Maryland-based university counted 100,047 deaths and 1,695,776 cases.
The US continues to lead in cases and deaths worldwide from the virus.
The UK has the second-highest number of fatalities at 37,542, followed by Italy with 33,072.
Nearly 385,000 patients have recovered in the US, according to the data.
New York remains the worst-hit state with 29,370 deaths and nearly 365,000 cases, followed by New Jersey with nearly 11,500 deaths and an excess of 156,000 cases.
According to the Centers for Disease Control and Prevention, more than 62,000 doctors, nurses and other healthcare workers have been sickened and nearly 300 have died from the virus.
The grim milestone came as all 50 states have begun to reopen two months after exhausting restrictions to stop the spread of the virus across the country.
Since the virus emerged last December in the Chinese city of Wuhan, it has spread to at least 188 countries and regions.
There are more than 5.6 million confirmed infections globally with more than 353,000 deaths, while an excess of 2.3 million patients have recovered.